Stuart Little is no ordinary mouse. Born to a family of humans he lives in New York City with his parents, his older brother George and Snowball the cat. He's an adventurous and heroic little mouse. When his best friend, a beautiful little bird called Margalo disappears from her nest, Stuart is determined to track her down. He ventures away from home for the very first time in his life and finds himself embroiled in one exciting adventure after another, making new friends and meeting old ones along the way.