Kelly Thompson, and her older sister, Meghan, are proof that sisterhood doesn't always equate to friendship. Kelly, an anxious child, looked to her big sister for protection, and Meghan, who was being treated for kidney cancer, adored her younger sister. But when, as a teenager, Meghan becomes addicted to cocaine and opioids, Kelly is forced to reevaluate her family role as her relationship with Meghan is torn apart. It's only when Meghan becomes a mother that she and Kelly tentatively begin to face past hurts and reexamine what sisterhood really means. Just as they reunite, Meghan is diagnosed with terminal cancer the day after the birth of her second child. Now, as the family reels at the prospect of the biggest loss, Kelly and Meghan will draw on their mutual dark sense of humour and deep understanding of each other, to share all they can in the time that they have.