In fourteen essays connected by theme and experience, Soriano traverses centuries and continents, weaving together memory and history, sociology and personal stories, neuroscience and public health, into a vivid tapestry of what it takes to transform trauma not just body by body, but through the body politic and ecosystems at large. Beginning with a shocking timeline juxtaposing Soriano’s medical history with the history of hysteria and witch hunts, Nervous navigates the human body—centering neurodiverse, disabled, and genderqueer bodies of color—within larger systems that have harmed and silenced Filipinos for generations. Soriano’s wide-ranging essays contemplate the Spanish-American War that ushered in United States colonization in the Philippines.