For decades Marie Curie was the only woman in the room at international scientific gatherings, and despite constant illness she travelled far and wide to share the secrets of radioactivity, a term she coined. She is still the only person to win a Nobel Prize in two scientific fields. Her ingenuity extended far beyond the laboratory walls; grieving the death of her husband, Pierre, she took his place as professor of physics at the Sorbonne, devotedly raised two daughters, drove a van she outfitted with x-ray equipment to the front lines of World War I, befriended Albert Einstein and inspired generations of young women to pursue science as a way of life. Sobel navigates her remarkable discoveries and fame alongside the women who became her legacy – from Norway’s Ellen Gleditsch and France’s Marguerite Perry, to her own daughter, Irene, a Nobel Prize winner in her own right.