Each chapter of this inventive consideration of American culture evokes an actual meeting between two historical figures. In 1854, Henry James, as a boy, goes with his father to have a daguerreotype made by Mathew Brady and is captured in a moment of self-consciousness about being American. Brady returns to photograph Walt Whitman and, later, at City Point in the midst of the Civil War, Ulysses S. Grant. Meanwhile, Henry James begins a lasting friendship with William Dean Howells, and also meets Sarah Orne Jewett, who in turn is a mentor to Willa Cather. Mark Twain publishes Grant's memoirs; and W. E. B. Du Bois and his professor William James visit the young Helen Keller. The accumulation of these pairings draws the reader into the mysterious process through which creativity has been sparked and passed on among iconoclastic American writers and artists.